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Updated: May 5, 2026
06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
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Stroke and climate change: A World Stroke Organization scientific statement.
Ali Saad1, Maria Khan2,3, Conrado J Estol4
1Climate & Health Program, University of Colorado Anschutz Medical School, Denver, CO, USA.
Summary
Climate change significantly increases stroke risk through extreme temperatures and weather events, impacting brain health globally. Addressing climate change is crucial for stroke prevention and protecting vulnerable populations.
Area of Science:
- Environmental Health
- Neurology
- Climate Science
Background:
- Climate change presents a growing threat to global brain health.
- It is increasingly linked to stroke incidence, outcomes, and health inequities.
- This statement reviews evidence on stroke and climate-exacerbated environmental variables.
Purpose of the Study:
- To summarize current evidence on the associations between stroke and environmental variables exacerbated by climate change.
- To focus on the impact of these variables on stroke risk and outcomes.
- To highlight implications for stroke prevention and care.
Main Methods:
- Systematic review of published studies on stroke and environmental variables (temperature, humidity, pressure, storms, weather events).
- Exclusion of air pollution unrelated to wildfire exposure.
- Evaluation of study design, sample size, geographic context, and evidence strength, with attention to vulnerable populations.
Main Results:
- Cold exposure, temperature variability, and extreme heat are consistently linked to increased stroke risk.
- Low barometric pressure, humidity shifts, and exposure to dust, sandstorms, and wildfire smoke also increase stroke incidence, especially in older adults and LMICs.
- Compound weather events can have additive or synergistic effects on stroke incidence and mortality.
Conclusions:
- Mitigation of greenhouse gas emissions is essential to reduce stroke risk drivers and protect brain health.
- Stroke professionals should advocate for climate action and integrate climate risk into clinical practice and health system planning.
- Strengthening global collaboration and climate resilience in stroke care systems is critical.
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