Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Latent Classes of Pain Treatment Utilization at a Tertiary Pain Clinic: A Cross-Sectional Study.

Pain medicine (Malden, Mass.)·2026
Same author

Patient-Centered Prescription Opioid Tapering Methods : A Randomized Clinical Trial.

Annals of internal medicine·2026
Same author

Applying an intersectional framework to characterize chronic pain disparities one year following traumatic spinal cord injury.

The journal of pain·2026
Same author

Pain Catastrophizing, Pain Self-Efficacy, and their Interaction as Predictors of Health Outcomes in Chronic Pain.

medRxiv : the preprint server for health sciences·2026
Same author

Ten simple rules for turning your qualifying exam into an NIH-style fellowship proposal: A guide for graduate students.

PLoS computational biology·2026
Same author

A multiverse approach to heat-evoked skin conductance analysis: evaluating the influence of analytic pipeline on associations between skin conductance and pain.

Pain·2026

Related Experiment Video

Updated: Jun 21, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

13.3K

Single Session Behavioral Interventions for Chronic Pain A Systematic Review and Meta Analysis of Randomized

Maisa S Ziadni1, Troy C Dildine1, Karlyn A Edwards2

  • 1Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford University, 1070 Arastradero Road, Suite 200, MC5596, Palo Alto, CA, 94304, USA.

The Journal of Pain
|March 16, 2026
PubMed
Summary

Single session interventions (SSIs) for chronic pain offer a scalable, low-burden approach. These psychological interventions effectively improve pain intensity, interference, and mental health outcomes in patients with chronic pain.

Keywords:
Chronic paindigitalpsychological/behavioral interventionssingle-sessionsystematic review

More Related Videos

Manual Therapy for a Chronic Non-Specific Low Back Pain Rat Model
07:34

Manual Therapy for a Chronic Non-Specific Low Back Pain Rat Model

Published on: August 11, 2023

1.2K
Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
08:33

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

1.9K

Related Experiment Videos

Last Updated: Jun 21, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

13.3K
Manual Therapy for a Chronic Non-Specific Low Back Pain Rat Model
07:34

Manual Therapy for a Chronic Non-Specific Low Back Pain Rat Model

Published on: August 11, 2023

1.2K
Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
08:33

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

1.9K

Area of Science:

  • Behavioral Medicine
  • Pain Management
  • Psychology

Background:

  • Chronic pain affects millions globally, necessitating scalable and effective treatment options.
  • Traditional behavioral treatments for chronic pain often involve multiple sessions, posing a burden to patients.
  • Single session interventions (SSIs) present a novel, less burdensome alternative for managing chronic pain.

Purpose of the Study:

  • To systematically review randomized controlled trials (RCTs) evaluating behavioral SSIs for chronic pain.
  • To synthesize the content, delivery, and impact of SSIs on psychological and physical outcomes.
  • To assess the quality and efficacy of SSIs in improving pain management.

Main Methods:

  • Systematic review of 17 RCTs identified through searches of seven electronic databases up to 11/2024.
  • Inclusion criteria: RCTs of psychological SSIs targeting pain in adults with chronic pain.
  • Quality assessment using NIH's Quality Assessment Tool for RCTs.

Main Results:

  • SSIs demonstrated efficacy in improving pain outcomes, with small but significant effects on pain intensity (SMD=0.17) and pain interference (SMD=0.27).
  • Significant reductions were observed in pain catastrophizing (SMD=0.37), anxiety (SMD=0.29), and depression (SMD=0.25).
  • 13 of 17 RCTs (76%) exhibited good internal validity.

Conclusions:

  • Behavioral SSIs are generally effective in improving pain and associated psychological outcomes across diverse chronic pain conditions.
  • SSIs offer a low-burden, accessible option for behavioral pain care, particularly when longer treatments are not feasible.
  • Future research should consider design and methodological recommendations for optimizing SSIs in chronic pain management.