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Methods of Medium Optimization01:28

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Optimizing growth media enhances microbial proliferation and maximizes product yield. Statistical experimental design methodologies provide structured and reproducible approaches, offering progressively higher levels of robustness and efficiency.The One-Factor-at-a-Time (OFAT) MethodThe One-Factor-at-a-Time (OFAT) method involves adjusting a single variable while keeping all others constant. However, it cannot detect interactions between variables, often leading to suboptimal outcomes when...
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Evaluation and Optimization of Azithromycin Removal by Raw and Alkali-Modified Peanut Shells Using Taguchi-Based

Rohab Asad1, Ghulam Hussain1, Muhammad Usman2

  • 1Institute of Environmental Engineering & Research, University of Engineering & Technology, Lahore, Punjab, Pakistan.

Water Environment Research : a Research Publication of the Water Environment Federation
|March 16, 2026
PubMed
Summary
This summary is machine-generated.

Peanut shell powder effectively removes the antibiotic azithromycin from water. Alkali modification significantly enhances removal efficiency, offering a sustainable and cost-effective solution for pharmaceutical pollution.

Keywords:
Taguchiadsorptionantibioticsazithromycinpeanut shells

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Area of Science:

  • Environmental Science
  • Materials Science
  • Chemical Engineering

Background:

  • Advanced antibiotic removal methods are costly, driving research into sustainable bio-adsorbents.
  • Peanut shell powder presents a novel, low-cost bio-adsorbent option for environmental remediation.

Purpose of the Study:

  • To evaluate raw and alkali-modified peanut shell powder for azithromycin removal.
  • To optimize adsorption parameters using a Taguchi-based experimental design.

Main Methods:

  • Characterization of adsorbents using FTIR and SEM-EDX.
  • Taguchi experimental design to optimize pH, initial concentration, adsorbent dose, and time.
  • Kinetic, isotherm, and surface analyses to understand adsorption mechanisms.

Main Results:

  • Raw peanut shell powder achieved 63% azithromycin removal under optimal conditions.
  • Alkali-modified peanut shell powder reached a maximum removal efficiency of 85%.
  • Optimized conditions for modified adsorbent: pH 11, 30 mg/L initial concentration, 60 min, 0.4 g/L dose.

Conclusions:

  • Alkali-modified peanut shells offer superior adsorption capacity (qmax = 192.1 mg/g vs. 159.2 mg/g).
  • Improved performance is attributed to increased surface heterogeneity and functional groups.
  • pH and initial concentration are key factors influencing azithromycin removal.