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Published on: July 4, 2018
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[Research Advances on Natural Products in Maintaining Oral Microecological Balance]
Yaqi Liu1, Qizhao Ma1, Mingmei Meng1
1（ 610041）State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China.
Summary
Natural products show promise for maintaining oral microecological balance, offering antibacterial and anti-inflammatory benefits. This review explores their potential in preventing and treating oral diseases by regulating microbial communities.
Area of Science:
- Microbiology
- Natural Products Chemistry
- Oral Health
Background:
- The oral cavity hosts a complex microecosystem with diverse microorganisms.
- Microbial balance is crucial for oral health; imbalance can lead to diseases and affect systemic health.
- Natural products possess properties like antibacterial, anti-inflammatory, and biofilm inhibition.
Purpose of the Study:
- To systematically review the characteristics of natural products.
- To elucidate their mechanisms in regulating oral microecological balance.
- To assess their application prospects and limitations in oral disease management.
Main Methods:
- Literature review of natural products and their effects on oral microecology.
- Analysis of mechanisms including antibacterial, anti-inflammatory, and quorum sensing inhibition.
- Evaluation of potential applications in preventing and treating oral diseases.
Main Results:
- Natural products exhibit diverse properties beneficial for oral microecology.
- Mechanisms involve direct antimicrobial action and modulation of microbial interactions.
- Potential exists for natural products in managing endodontic and periodontal diseases.
Conclusions:
- Natural products are valuable for maintaining oral microecological balance.
- Further research is needed to optimize their application in clinical settings.
- Natural products offer a promising avenue for oral disease prevention and treatment.
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