Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Study Designs in Epidemiology01:20

Study Designs in Epidemiology

1.4K
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
1.4K
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

201
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
201

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute non-alcoholic caffeinated beverage consumption as a trigger for cryptogenic ischemic stroke in the young: findings from the SECRETO study.

Journal of neurology·2026
Same author

Prevalence of circulating hepatitis C virus genotypes and drug-resistant variants in former Soviet Union countries: a scoping review with genotype meta-analysis.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026
Same author

Mediastinal over-staging with PET-CT in tuberculosis-endemic locally advanced NSCLC: SUV threshold recalibration improves PET/EBUS concordance.

European journal of nuclear medicine and molecular imaging·2026
Same author

Qualitative study of barriers and facilitators to Dietary Approaches to Stop Hypertension (DASH) on the Caribbean island of Montserrat.

BMJ public health·2026
Same author

Association Between Physical Activity and Cryptogenic Ischemic Stroke in Young Adults: A Case-Control Study.

European journal of neurology·2026
Same author

Pharmacy professional's research readiness in practice: findings from four co-produced cross-sectional surveys within NHS health trusts in England.

The International journal of pharmacy practice·2026

Related Experiment Video

Updated: Mar 17, 2026

The Stroke Preclinical Assessment Network Multi-laboratory Model of Thromboembolic Stroke with Thrombolysis: TE-MCAo
05:46

The Stroke Preclinical Assessment Network Multi-laboratory Model of Thromboembolic Stroke with Thrombolysis: TE-MCAo

Published on: December 19, 2025

364

United Kingdom Young Stroke Study (UKYSS): study protocol for an ambispective observational study.

Phillip Wilford Ferdinand1,2, Ram Bajpai2, Mohammed Shoaib1

  • 1Neurosciences, Royal Stoke University Hospital, Stoke-on-Trent, England, UK.

BMJ Neurology Open
|March 16, 2026
PubMed
Summary

Young stroke incidence is rising in the UK. This study, the United Kingdom Young Stroke Study (UKYSS), investigates causes and outcomes to improve prevention strategies for young adults (18-49).

Keywords:
STROKE

More Related Videos

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
09:59

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

14.7K
Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
08:53

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

Published on: June 6, 2025

2.0K

Related Experiment Videos

Last Updated: Mar 17, 2026

The Stroke Preclinical Assessment Network Multi-laboratory Model of Thromboembolic Stroke with Thrombolysis: TE-MCAo
05:46

The Stroke Preclinical Assessment Network Multi-laboratory Model of Thromboembolic Stroke with Thrombolysis: TE-MCAo

Published on: December 19, 2025

364
A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
09:59

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

14.7K
Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
08:53

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

Published on: June 6, 2025

2.0K

Area of Science:

  • Neurology
  • Public Health
  • Epidemiology

Background:

  • 10-15% of all strokes occur in young adults (18-49 years).
  • UK young stroke incidence is increasing, with diverse causes and significant risk factors.
  • Long-term functional and psychological issues are common in young stroke survivors.

Purpose of the Study:

  • To gather representative data on young stroke patients in the UK.
  • To develop a prognostic tool for primary and secondary stroke prevention in young adults.
  • To understand the long-term sequelae of strokes in this demographic.

Main Methods:

  • An ambispective observational study (UKYSS) of first-ever ischaemic or haemorrhagic strokes in adults aged 18-49.
  • Data collection on demographics, risk factors, clinical details, investigations, and outcomes.
  • Statistical analysis including descriptive statistics, Kaplan-Meier curves, and Cox proportional hazards models for prognostic assessment.

Main Results:

  • Data collection ongoing for strokes between 2013-2020.
  • Analysis will identify risk factors and develop a validated prognostic model.
  • Patient-reported outcomes on functional domains will be collected via questionnaire.

Conclusions:

  • The UKYSS aims to provide crucial insights into young stroke aetiology and prognosis.
  • Findings will inform the development of targeted prevention and management strategies.
  • This research will contribute to reducing the burden of stroke in young adults.