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Updated: Mar 17, 2026

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
Published on: September 24, 2021
Perioperative and Surgical Management of Constrictive Pericarditis
Lamis El Harake1, Mohamed Al-Kazaz1, Paul C Cremer1
1Bluhm Cardiovascular Institute, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Surgical pericardiectomy offers definitive treatment for constrictive pericarditis, a diastolic heart failure. Patient selection and radical resection improve outcomes, while disease etiology and dysfunction impact results.
Area of Science:
- Cardiology
- Cardiac Surgery
- Pericardial Diseases
Background:
- Constrictive pericarditis causes diastolic heart failure due to pericardial rigidity.
- Surgical pericardiectomy is the primary treatment for chronic or refractory cases.
- Outcomes are variable, influenced by disease factors and surgical approach.
Purpose of the Study:
- To review current best practices for surgical management of constrictive pericarditis.
- To emphasize patient selection, timing, operative approach, and perioperative care.
- To highlight factors influencing surgical outcomes.
Main Methods:
- Review of contemporary literature on surgical pericardiectomy.
- Emphasis on diagnostic differentiation and risk stratification.
- Discussion of multimodality imaging in diagnosis and planning.
Main Results:
- Radical pericardiectomy yields better functional recovery than partial resection.
- Disease etiology, chronicity, myocardial involvement, and end-organ dysfunction affect prognosis.
- Radiation-associated disease and mixed physiology correlate with poorer outcomes.
Conclusions:
- Accurate diagnosis and risk stratification are crucial for surgical decision-making.
- Patient selection, radical resection, and high-volume centers optimize results.
- Careful perioperative management is essential for successful surgical pericardiectomy.
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