Related Experiment Video
Updated: Mar 17, 2026

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
Published on: September 24, 2021
Perioperative and Surgical Management of Constrictive Pericarditis
Lamis El Harake1, Mohamed Al-Kazaz1, Paul C Cremer1
1Bluhm Cardiovascular Institute, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Insights
Surgical pericardiectomy offers definitive treatment for constrictive pericarditis, a diastolic heart failure. Patient selection and radical resection improve outcomes, while disease etiology and dysfunction impact results.
Area of Science:
- Cardiology
- Cardiac Surgery
- Pericardial Diseases
Background:
- Constrictive pericarditis causes diastolic heart failure due to pericardial rigidity.
- Surgical pericardiectomy is the primary treatment for chronic or refractory cases.
- Outcomes are variable, influenced by disease factors and surgical approach.
Purpose of the Study:
- To review current best practices for surgical management of constrictive pericarditis.
- To emphasize patient selection, timing, operative approach, and perioperative care.
- To highlight factors influencing surgical outcomes.
Main Methods:
- Review of contemporary literature on surgical pericardiectomy.
- Emphasis on diagnostic differentiation and risk stratification.
- Discussion of multimodality imaging in diagnosis and planning.
Main Results:
- Radical pericardiectomy yields better functional recovery than partial resection.
- Disease etiology, chronicity, myocardial involvement, and end-organ dysfunction affect prognosis.
- Radiation-associated disease and mixed physiology correlate with poorer outcomes.
Conclusions:
- Accurate diagnosis and risk stratification are crucial for surgical decision-making.
- Patient selection, radical resection, and high-volume centers optimize results.
- Careful perioperative management is essential for successful surgical pericardiectomy.
Abstract:
Constrictive pericarditis represents a form of severe diastolic heart failure characterized by impaired diastolic filling due to a rigid, noncompliant pericardium. Surgical pericardiectomy is the definitive treatment for chronic or refractory subacute constrictive pericarditis; however, outcomes vary widely depending on disease etiology, chronicity, myocardial involvement, end-organ dysfunction, and surgical technique. This review summarizes contemporary best practices for the surgical management of constrictive pericarditis, with emphasis on patient selection, timing of intervention, operative approach, and perioperative considerations. Accurate differentiation between inflammatory, transient constrictive phenotypes and irreversible fibrotic disease is central to therapeutic decision-making. Etiology-based risk stratification, assessment of hepatic and renal dysfunction, and careful evaluation of myocardial involvement provide critical prognostic information. Multimodality imaging plays a central role in diagnosis, surgical planning, and identification of patients most likely to benefit from intervention. Radical pericardiectomy is associated with superior functional recovery compared with partial resection, whereas radiation-associated disease, mixed constrictive-restrictive physiology, and advanced end-organ dysfunction are consistently linked to worse outcomes. High-volume centers of excellence in pericardial disease are critical in optimizing results after radical pericardiectomy.
More Related Videos
Related Concept Videos
Pericarditis III: Medical Management
Pericarditis IV: Nursing Management
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiomyopathy V: Interprofessional Care
Myocarditis III: Medical Management
Mitral Stenosis III: Medical Management

