Hypertension Management Beyond Blood Pressure Control in India: An Expert Consensus on Angiotensin II Receptor

Jagdish Hiremath1, Ashok Kirpalani2, Deodatta Chafekar3

  • 1Cardiology, Ruby Hall Clinic, Pune, IND.

Cureus
|March 16, 2026
PubMed

Insights

Effective hypertension management in India requires addressing comorbidities like cardiovascular disease, chronic kidney disease, and type 2 diabetes. Expert consensus highlights combination therapy, including telmisartan and cilnidipine, for improved outcomes.

Area of Science:

  • Cardiology
  • Nephrology
  • Internal Medicine

Background:

  • Hypertension is a major global cause of cardiovascular morbidity and mortality, with low control rates in India.
  • Effective management necessitates addressing comorbidities like cardiovascular disease (CVD), chronic kidney disease (CKD), and type 2 diabetes mellitus (T2DM).

Purpose of the Study:

  • To develop an expert consensus on comprehensive hypertension management in India.
  • To review current evidence on pharmacological and non-pharmacological interventions, including combination therapy for hypertension with comorbidities.

Main Methods:

  • Multidisciplinary expert panel convened six advisory board meetings.
  • Comprehensive literature review of RCTs and systematic reviews (2019-2025) from PubMed and Google Scholar.
  • Focused on hypertension management, combination therapy, and comorbidity-specific strategies.

Main Results:

  • Emphasized early screening for hypertension-mediated organ damage.
  • Combination therapy, particularly telmisartan and cilnidipine, showed improved BP control, reduced proteinuria, and organ protection.
  • Endorsed non-pharmacological interventions and fixed-dose combinations for adherence.

Conclusions:

  • Supports a comprehensive, patient-centered approach to hypertension management in India.
  • Telmisartan and cilnidipine combination shows potential benefits beyond BP reduction, based on current evidence.
  • Further large-scale outcome trials are needed to confirm clinical benefits.

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