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Malignant Small Bowel Neoplasms: A 20-Year Retrospective Analysis in a Tertiary Center
Ana Teresa Ferreira1, Joana Mesquita2, Marta Rocha1
1Department of Gastroenterology, Unidade Local de Saúde de Santo António, Porto, Portugal.
Malignant small bowel neoplasms are rare but increasing. Over 20 years, diagnosis shifted from adenocarcinoma to neuroendocrine tumors, with improved survival in recent years.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Malignant small bowel neoplasms are rare and diverse, posing diagnostic challenges.
- Their incidence is rising, increasing clinical and research interest.
Purpose of the Study:
- To describe demographic and clinical characteristics of small bowel neoplasms.
- To analyze diagnostic evolution over 20 years in a tertiary center.
Main Methods:
- Retrospective single-center study (2001-2020).
- Inclusion of 135 patients with malignant small bowel neoplasms.
- Statistical analysis using SPSS v29.0.
Main Results:
- Adenocarcinomas (31.1%) and neuroendocrine tumors (28.1%) were most common.
- Most patients (80.7%) were symptomatic; 55.4% had severe complications.
- Diagnosis shifted from adenocarcinoma (2001-2010) to neuroendocrine tumors (2011-2020).
Conclusions:
- A 20-year cohort reveals diagnostic shifts and improved survival.
- Increased incidence of neuroendocrine tumors correlates with better survival rates.
- Histological type distribution significantly changed over the study period.
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