Related Experiment Video
Updated: Mar 18, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
Improving the Algorithm: The Inclusion of a Socioeconomic Status Measure in Predicting Type 2 Diabetes Development in
Subin Jang1,2, Yinzhao Wang3, Sisi Ma3,4
1Center for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN.
Objective:
To evaluate whether the Area Deprivation Index (ADI) contributes to predicting type 2 diabetes development in youth with prediabetes compared with a machine learning (ML) model built with other data elements.
Research Design And Methods:
Patient encounters (n = 665) from an electronic medical record were used to build supervised ML models to predict type 2 diabetes development within 1 year of prediabetes diagnosis. The ADI was constructed using patients' census block data. Two models, trained on data with and without ADI, were built. The model selection resulted in logistic regressions with 1) HbA1c only and 2) HbA1c + ADI as the best models from each data set.
Results:
A total of 181 patient encounters (27.2%) developed type 2 diabetes. The area under the receiver operating characteristic curve of the HbA1c-only model was 0.68 and of the HbA1c + ADI model, 0.73.
Conclusions:
The addition of ADI to the model resulted in the best performance in predicting youth-onset type 2 diabetes development.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes: Symptoms, Diagnosis, and Complications
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Lifestyle Factors and Health
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...

