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Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
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Inhaled Antibiotics to Treat Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis

Shan Lyu1, Jian Luo2, Ping Liu3

  • 1Department of Critical Care Medicine, Peking University People's Hospital, Beijing, China.

Critical Care Medicine
|March 16, 2026
PubMed
Summary

Adjunctive inhaled antibiotics significantly improve clinical cure and microbiological eradication for ventilator-associated pneumonia (VAP). These treatments may also reduce mortality, especially in VAP-only patients, offering potential benefits over intravenous therapy.

Keywords:
aerosol drug therapyinhaled antibioticsmeta-analysistreatmentventilator-associated pneumonia

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