Related Experiment Video

Updated: Mar 18, 2026

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

A data-driven method for research trend analysis in a scientific discipline: Application to the journal of biomedical

Yilu Fang¹, Gongbo Zhang¹, Samir Sanchez Tejada¹

¹Columbia University, New York, NY, USA.

Journal of Biomedical Informatics

|March 16, 2026

Abstract

Objective:

Accurately characterizing research trends is critical for identifying cutting-edge scientific breakthroughs in their infancy and informing strategic priorities. This research contributes a pipeline that utilizes generative AI technologies to develop research topic taxonomies from publication keywords and analyze keyword evolution within topics, methodological and domain trends, and topic co-occurrences. We demonstrated the pipeline by conducting a retrospective analysis of biomedical informatics research trends in the Journal of Biomedical Informatics (JBI).

Methods:

We identified the JBI publications with keywords available on PubMed, spanning 2011-2025. We downloaded all the keywords and categorized them into methodological innovations and health domains, identified topics, assigned topic names, and constructed their hierarchies, all using large-language models (LLMs). We introduced an automated method for evaluating topics, leveraging MeSH terminology as the underlying knowledge base.

Results:

Using 6,930 unique keywords from 2,427 publications, we derived 1,028 distinct topics related to methodological innovations, with each topic associated with medians of four keywords (Q1: 2, Q3: 13) and six publications (Q1: 2, Q3: 19). We identified 904 topics related to health domains, with each topic associated with three keywords (Q1: 1, Q3: 11) and four publications (Q1: 1, Q3: 15). Based on the topics, we analyzed the prominent research areas, trends in publication volume, evolution of keyword distributions within each topic, and patterns of co-occurring topics. Among the 2,379 eligible publications, 2,009 (84.4%) exhibited overlap between the keyword-derived MeSH terms and the MeSH terms assigned to the publication by the National Library of Medicine.

Conclusion:

This study presents a method that leverages modern generative AI technologies for retrospective analysis of a scientific field to identify emerging topics and to detect shifts in scholarly focus. Illustrated by data for JBI and correlated with historical background events and policy changes, our findings demonstrate the effectiveness and utility of the methods while providing a powerful lens to understand the evolution of biomedical informatics research priorities in JBI.

Keywords:

Bibliometric analysis Biomedical informatics Large language models Scientific topic trend analysis

More Related Videos

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

A User-friendly and Powerful R Analysis of Large-scale Datasets

A User-friendly and Powerful R Analysis of Large-scale Datasets

Published on: November 4, 2025

Related Concept Videos

Psychology as a Science

Psychology as a Science

Psychology, as a scientific discipline, aims to understand the mind and behavior through rigorous and systematic methods. The foundation of psychological research is evidence-based, relying heavily on the scientific method to derive and validate knowledge. This structured approach ensures that findings are reliable, valid, and applicable to broader contexts.
The scientific method in psychology involves six critical steps: making observations, formulating hypotheses, conducting tests, analyzing...

The Scientific Method in Nursing Process

The Scientific Method in Nursing Process

The scientific method provides the foundation for any research. It is the most reliable and objective of all forms of gaining knowledge and guides in applying research-based evidence in practice and conducting future research.
When using research findings to change practice, one must understand the process used to guide a study. The scientific method is a systematic, step-by-step process that supports the data's validity, reliability, and generalizability. As a result, findings can be...

Scientific Nature of Social Psychology

Scientific Nature of Social Psychology

Social psychology is a scientific discipline dedicated to understanding how individuals think, feel, and behave in social contexts. Unlike common sense, which relies on anecdotal experiences and intuition, social psychology employs systematic research and empirical methods to ensure objectivity and reliability. This distinction is fundamental in distinguishing scientifically supported findings from mere speculation.Four fundamental scientific values guide a structured approach to research in...

The Scientific Method

The Scientific Method

Research is what makes the difference between facts and opinions. Facts are observable realities, and opinions are personal judgments, conclusions, or attitudes that may or may not be accurate. In the scientific community, facts can be established only using evidence collected through empirical research.

The Scientific Method

The Scientific Method

The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...

The Scientific Method

The Scientific Method

Chemistry is an empirical science. Scientists often pose questions to understand the chemistry in everyday life and seek answers to these questions. To achieve this, scientists follow a definitive series of steps that together make up the Scientific Method. This approach involves making observations, asking questions, building a hypothesis, conducting experiments, analyzing results, and forming a conclusion.

Articles linked to this work by shared authors, journal, and citation graph.

Large language model-based extraction of rheumatoid arthritis clinical disease activity index from clinical notes.

JAMIA open·2026

PhenoSS: phenotype semantic similarity-based approach for rare disease prediction and patient clustering.

Journal of the American Medical Informatics Association : JAMIA·2026

Tutorial: guidance on the use of large language models for medical research.

Nature protocols·2026

Inherited Susceptibility to Urinary Tract Infections from Kidney Papilla to Bladder.

medRxiv : the preprint server for health sciences·2026

Preferences of research participants with experience receiving individual results for future return of results.

Journal of clinical and translational science·2026

RankVar: machine learning-based variant ranking and reinterpretation for rare genetic diseases.

Genome medicine·2026

See all related articles