Related Experiment Video
Updated: Mar 18, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
Published on: April 28, 2022
An adapted brief negotiation interview for alcohol and cannabis use among assault-injured emerging adults: A
Edouard Coupet1, James Dodington2, Gail D'Onofrio3
1Department of Emergency Medicine, Yale School of Medicine, United States of America; Center for Injury and Violence Prevention, Yale New Haven Hospital, United States of America.
Abstract:
Emerging adults are disproportionately at risk for substance misuse and assault injury. Assault-injured emerging adults with substance misuse have increased risk of morbidity and mortality compared to those without and often receive care in the Emergency Department (ED). This manuscript describes the development of a protocol for a pilot randomized trial of an adapted brief behavioral intervention, the Brief Negotiation Interview (BNI), for use among assault-injured emerging adults with alcohol and/or cannabis misuse presenting to the ED. First, we will perform a mixed methods study of assault-injured emerging adults with alcohol and/or cannabis misuse to elicit the shared psychosocial risk factors that contribute to both alcohol and/or cannabis misuse in the context of assault injury. We will then use these data to adapt the BNI for use among assault-injured emerging adults with alcohol and/or cannabis misuse. We will evaluate the feasibility and acceptability of the adapted BNI in a randomized trial in the ED setting (N = 50). This pilot study is a critical initial step in developing an effective brief behavioral intervention for reducing alcohol and cannabis use among assault-injured emerging adults. Trial Registration Number NCT07070414.

