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Real-time reconstruction of 3D bone models via very-low-dose protocols
Yiqun Lin1, Haoran Sun2, Yongqing Li3
1Department of Electronic and Computer Engineering, The Hong Kong University of Science and Technology, Hong Kong SAR, China.
NPJ Digital Medicine
|March 17, 2026
Summary
A new AI framework reconstructs patient bone models from X-rays in 30 seconds, offering a faster, safer alternative to CT scans for surgical planning and intraoperative guidance.
Area of Science:
- Orthopedic surgery
- Medical imaging
- Artificial intelligence in medicine
Background:
- Patient-specific bone models are crucial for surgical planning and guide design.
- Current CT-based methods are time-consuming, involve high radiation, and are limited to preoperative use.
- Manual delineation of bone structures is labor-intensive and prone to error.
Purpose of the Study:
- To introduce a novel AI framework, Semi-Supervised Reconstruction with Knowledge Distillation (SSR-KD).
- To enable rapid and accurate reconstruction of high-quality bone models from biplanar X-rays.
- To reduce reliance on CT scans and manual segmentation for orthopedic applications.
Main Methods:
- Developed SSR-KD, an AI framework utilizing knowledge distillation for semi-supervised learning.
- Trained the model on biplanar X-ray data to reconstruct 3D bone models.
- Evaluated model accuracy with an average error under 1.0 mm.
- Conducted high tibial osteotomy simulations using reconstructed models.
Main Results:
- SSR-KD reconstructs bone models from biplanar X-rays in approximately 30 seconds.
- Achieved an average reconstruction error of less than 1.0 mm.
- Expert simulations showed comparable clinical applicability to CT-derived bone models.
- Demonstrated significant acceleration and reduced radiation exposure compared to traditional methods.
Conclusions:
- SSR-KD provides a fast, accurate, and low-radiation alternative for creating patient-specific bone models.
- The AI framework enhances the practicality of bone models for both preoperative planning and potential intraoperative guidance.
- This technology has transformative potential for orthopedic surgery and patient care.

