Multidisciplinary Care of Patients With Penile Cancer

Area of Science:

• Oncology
• Urology
• Public Health

Background:

• Penile squamous cell carcinoma (PSCC) is a rare malignancy with significant disparities in incidence, care access, and outcomes.
• PSCC is associated with high treatment morbidity, social stigma, and psychological distress.

Purpose of the Study:

• To provide a comprehensive overview of penile squamous cell carcinoma.
• To integrate epidemiology, pathology, imaging, and multimodal management strategies for PSCC.

Main Methods:

• Review of epidemiological data, histopathologic features, and imaging modalities for PSCC staging.
• Discussion of multimodal management including surgery (lymph node dissection, sentinel lymph node biopsy), radiotherapy, and systemic therapies.
• Exploration of patient advocacy, psychosocial support, and disparities in care.

Main Results:

• Penile cancer staging principles and histopathologic features are crucial for management.
• Imaging plays a key role in local staging of the primary tumor and nodal disease.
• Multimodal management, including surgical, radiological, and systemic approaches, is central to PSCC treatment.

Conclusions:

• Improving PSCC care necessitates a multidisciplinary approach, patient-centered advocacy, and global initiatives.
• Addressing disparities in care and quality of life is essential.
• Centralized cancer care models are important for advancing PSCC management.