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Updated: Jul 16, 2026

Three-dimensional Optical-resolution Photoacoustic Microscopy
Published on: May 3, 2011
Super-resolution pulse-echo imaging via 3D-printed phase-type acoustic meta-lens
Ji-Fan Qiu1, Zong-Lin Li2, Long-Sheng Zeng3
1School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515, China; State Key Laboratory of Biomedical Imaging Science and System, Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Researchers developed a 3D-printed meta-lens using genetic algorithms to achieve super-resolution ultrasound imaging, breaking the traditional diffraction limit for enhanced biomedical diagnostics and non-destructive testing.
Area of Science:
- Acoustics
- Metamaterials
- Imaging Technologies
Background:
- Overcoming the wave diffraction limit is crucial for advancing acoustic imaging.
- Super-resolution imaging offers enhanced detail beyond classical limits.
Purpose of the Study:
- To propose a novel meta-lens for achieving subwavelength ultrasound focusing.
- To surpass the conventional 0.5λ resolution limit in acoustic imaging.
Main Methods:
- Genetic algorithm-driven design of a meta-lens.
- Fabrication of the meta-lens using high-precision 3D printing.
- Quantitative point spread function measurements for validation.
Main Results:
- Achieved subwavelength ultrasound focusing in the far field (>20λ).
- Demonstrated a lateral full width at half maximum of 0.42λ, surpassing the 0.5λ limit.
- Validated super-resolution performance and superiority over Fresnel lenses.
Conclusions:
- The developed meta-lens offers a practical and scalable strategy for super-resolution acoustic devices.
- This technology has significant potential for biomedical diagnostics and non-destructive testing.
- Integration of metamaterial design and 3D printing enables advanced functional devices.

