Related Experiment Video For chromosomal microarray

Updated: Mar 19, 2026

FISH for Pre-implantation Genetic Diagnosis
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FISH for Pre-implantation Genetic Diagnosis

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Experiences With Detection of Higher-Copy Sex Chromosome Aneuploidy by cfDNA Screening: The Critical Role of

Lauren A Choate1, Courtney Studwell1, David T Miller1,2

  • 1Division of Cytogenetics, Center for Advanced Molecular Diagnostics, Department of Pathology, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, USA.

American Journal of Medical Genetics. Part A
|March 18, 2026
PubMed

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In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
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Keywords:
chromosomal microarraynoninvasive prenatal cell‐free DNA screeningsex chromosome aneuploidy