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An open B-mode ultrasound database for deep learning-based atherosclerotic plaque segmentation
Valeria S Rulloni1, Hernan A Perez2, Trinidad Dori3
1Facultad de Ciencias Exactas, Físicas y Naturales, Universidad Nacional de Córdoba, Córdoba, Argentina. vrulloni@unc.edu.ar.
Insights
A new open-access dataset of B-mode ultrasound images aids atherosclerotic plaque segmentation. This resource supports the development of automated methods for early cardiovascular disease diagnosis and risk assessment.
Area of Science:
- Medical imaging
- Cardiovascular disease research
- Artificial intelligence in healthcare
Background:
- Cardiovascular events cause significant global mortality, with atherosclerosis being a primary driver.
- Accurate detection of atherosclerotic plaques in medical images is crucial for early diagnosis and management.
- Manual plaque annotation in ultrasound images is time-consuming and prone to variability.
Purpose of the Study:
- To introduce a novel, open-access B-mode ultrasound image database for atherosclerotic plaque segmentation.
- To address the scarcity of annotated datasets for developing automated segmentation algorithms.
- To facilitate standardized and reproducible plaque analysis.
Main Methods:
- A dataset of 541 B-mode ultrasound images (800x800 pixels) with expert-validated binary segmentation masks was created.
- The dataset encompasses diverse imaging conditions, including plaque-free, single-plaque, and multiple-plaque scenarios.
- A U-Net ensemble model was trained and evaluated using the developed dataset.
Main Results:
- The U-Net ensemble achieved a median error of 0.35 mm² on plaque-free images.
- A mean Dice coefficient of 0.62 was obtained on images containing atherosclerotic plaques.
- The dataset demonstrated suitability for training and evaluating plaque segmentation algorithms.
Conclusions:
- The presented open-access database is valuable for developing and benchmarking automated atherosclerotic plaque segmentation tools.
- This resource can improve the standardization and reproducibility of plaque detection in B-mode ultrasound.
- The dataset supports advancements in early cardiovascular disease diagnosis and risk stratification.
Abstract:
Cardiovascular events, predominantly ischemic, account for approximately 32% of global mortality and are expected to increase approximately 30% by 2030. A substantial proportion of these events is preventable through the control of established risk factors. Atherosclerosis is defined by the progressive development of arterial plaques and remains the main cause of ischemic cardiovascular disease. In this context, plaque detection in medical images is required for early diagnosis and longitudinal assessment, which is commonly based on total plaque area. Manual plaque annotation in B-mode ultrasound images requires specialized expertise and is affected by inter- and intra-operator variability. Automatic methods trained on expert-annotated data are therefore required to improve standardization and reproducibility. However, the research community faces a limited availability of open access databases designed for image segmentation and benchmarking under traditional and heterogeneous imaging conditions inherent to B mode ultrasound data. This work presents an open-access B-mode ultrasound image database designed for atherosclerotic plaque segmentation. The dataset includes 541 ultrasound images with a resolution of 800 × 800 pixels, each paired with a binary segmentation mask validated by clinical specialists. The database captures heterogeneous imaging conditions, including plaque-free cases, single and multiple plaques, and non-centralized plaque locations. To assess its suitability for algorithm development, the dataset was used to train a U-Net ensemble. The evaluation provided a median error of 0.35 mm2 on plaque free test images and a mean Dice coefficient of 0.62 on test images containing plaques.
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