Thematic evolution and research trends in chemotherapy-induced peripheral neuropathy: a bibliometric and visual...

Chemotherapy-induced peripheral neuropathy (CIPN) significantly impacts patients' quality of life and treatment adherence. Despite the growing research on CIPN, bibliometric analyses remain scarce, limiting understanding of the field.

A bibliometric analysis of CIPN-related publications was conducted using records retrieved from the Web of Science Core Collection. Publications from 1992 to 2024 were included. CiteSpace, VOSviewer, and Bibliometrix were applied to analyze publication outputs, citation patterns, co-citation networks, keyword co-occurrence and clustering, collaboration networks among countries, institutions, and authors, and thematic evolution.

The bibliometric analysis identified approximately 3398 studies published since 1992, involving 87 countries, 4126 institutions, and 15,611 authors. The USA leads in both publication output and collaborations. Keyword analysis identified terms such as "neuropathic pain," "breast cancer," and "quality of life," and thematic maps highlighted motor themes.

CIPN research has grown steadily, shifting its focus from neurotoxicity to supportive care. Future research will likely focus on biological mechanisms and improved rehabilitation.