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Pleural effusions: seeing transudate-exudate differentiation in a different light.
David J Feller-Kopman1, Craig A Mounsey2
1Pulmonary and Critical Care Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA.
ERJ Open Research
|March 18, 2026
Summary
A new "triple combination" test for diagnosing pleural effusions eliminates the need for simultaneous serum sampling. This novel approach demonstrates diagnostic performance comparable to the established Light's criteria.
Area of Science:
- Medical Diagnostics
- Pulmonology
- Clinical Chemistry
Background:
- Light's criteria are the standard for diagnosing pleural effusions but require simultaneous serum and pleural fluid sampling.
- Simultaneous sampling can be logistically challenging and may delay diagnosis.
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