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Updated: Mar 19, 2026
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Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues
Published on: April 26, 2024
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Assessment of Microhardness on Root Canal Dentin Using Chelating Agents: A Comparative Study.
Anandamoy Bagchi1, Kapil R Jadhav2, Chitharanjan Shetty3
1Department of Pediatric and Preventive Dentistry, Kalinga Institute of Dental Sciences (KIDS), Campus 5, KIIT (DU), Patia, Bhubaneswar, Odisha, India.
Journal of Pharmacy & Bioallied Sciences
|March 18, 2026
Summary
QMix minimally reduced root canal dentin microhardness compared to EDTA and Citric Acid. This finding suggests QMix may better preserve dentin integrity during endodontic procedures.
Area of Science:
- Endodontics
- Dental Materials Science
Background:
- Root canal dentin microhardness is crucial for endodontic treatment success.
- Understanding the impact of chelating agents on dentin is vital for clinical practice.
Purpose of the Study:
- To compare the effects of EDTA, Citric Acid, and QMix on root canal dentin microhardness.
- Evaluate the potential of different chelating agents to preserve dentin integrity.
Main Methods:
- Thirty human premolars were divided into three groups: EDTA (17%), Citric Acid (10%), and QMix.
- Vickers microhardness testing was employed to measure dentin hardness.
- ANOVA and post hoc tests were used for statistical analysis.
Main Results:
- All tested chelating agents significantly reduced dentin microhardness.
- EDTA caused the most substantial decrease in microhardness, followed by Citric Acid.
- QMix demonstrated the least reduction in dentin microhardness.
Conclusions:
- QMix appears to be the least detrimental to root canal dentin microhardness.
- QMix may offer an advantage in maintaining dentin integrity during endodontic procedures.
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