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Pregnancy and Lactation Associated Osteoporosis: A Systematic Review

Zeinab Issa1, Randa Saad1, Younes Lama1

  • 1Calcium Metabolism and Osteoporosis Program, WHO Collaborating Center for Metabolic Bone Disorders, Faculty of Medicine, American University of Beirut-Medical Center, Beirut, Lebanon.

Calcified Tissue International
|March 18, 2026
PubMed
Summary

Pregnancy and lactation-associated osteoporosis (PLO) causes fragility fractures in young women, often during lactation. Vertebral fractures are most common, with a significant risk of recurrence in future pregnancies.

Keywords:
Actation/breastfeedingFragility fracturesPregnancy and lactation-associated osteoporosis (PLO)Systematic review

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