Exposure to parental depression in childhood and memory trajectories in mid- and later life
Related Experiment Video
Updated: Mar 20, 2026

Chronic Social Defeat Stress in Early Adolescent Male Mice
Published on: January 24, 2025
Zhenmei Zhang1, Seung-Won Emily Choi2, Yu Guo3,4
1Department of Sociology, Michigan State University, East Lansing, Michigan, United States of America.
Abstract:
Little is known about whether childhood exposure to parental mental health problems, a significant stressor in early life, influences an individual's memory trajectories in mid- and later life. Drawing on data from four waves (2011-2018) of the China Health and Retirement Longitudinal Study (CHARLS) and its supplement, the 2014 Life History Survey, we used the latent growth curve modeling technique to investigate whether exposure to parental depression in childhood is associated with memory trajectories of Chinese older adults. Our analytic sample included 7,097 respondents aged 50 and above who were raised by both parents. Results show that individuals who recalled having both parents depressed during their childhood had lower memory scores at baseline compared to their non-exposed counterparts, even after controlling for childhood socioeconomic status and health. These differences remained stable over the 7-year follow-up. Educational attainment and adult health-particularly depressive symptoms-explained the lower episodic memory scores observed in individuals who experienced both parents' depression during childhood. Surprisingly, individuals who reported having only one parent (either mother or father) depressed during their childhood did not show significantly different memory trajectories compared to their non-exposed counterparts. The findings underscore the long arm of parental mental health on cognitive function in later life and highlight the importance of preventing and treating parental depression through a child's formative years.
More Related Videos
04:20Author Spotlight: Exploring Microglial Interactions with Stress-Response Circuitry Using the Limited Bedding and Nesting Model
Published on: July 12, 2024
11:31Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
Published on: November 30, 2015
Related Concept Videos
Relationship with Parents: Attachment
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Psychological and Sociocultural Causes of Schizophrenia
Theory of Romantic Attachment in Adulthood
Repressed Memory