Trend and burden of lower-limb amputations due to diabetes: time series analysis, Amazonas, 2012-2021

To calculate the temporal trend and the burden of disease for lower-limb amputations due to diabetes in Amazonas, Brazil, from 2012 to 2021.

This is a time series analysis study using data from the Hospital Information System of the Brazilian Unified Health System. Specific and age-adjusted rates, the annual percent change of amputations, and the 95% confidence interval were calculated for the period 2012-2021. Years lived with disability were calculated and stratified by sex and age group between 2017 and 2021.

During the 10 years analyzed, 3,621 lower-limb amputation procedures were performed in people with diabetes in public hospitals in Amazonas. An increase in age-adjusted amputation rates among men was observed, rising from 8.33 per 100 thousand men in 2012 to 15.55 per 100 thousand men in 2021, with an annual percent change of 10.5% and a 95% confidence interval between 3.8% and 17.6%. The disease burden totaled 21,845.11 years lived with disability, of which 70.4% corresponded to men. Most years lived with disability were concentrated in the 45-64 age group (58.2%).

There was a male predominance in the increasing trend of lower-limb amputations and in the high burden of disease in Amazonas.