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The Tumor Microenvironment

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

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Related Experiment Video

Updated: Mar 20, 2026

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma

Published on: May 24, 2024

Decoding the tumor microenvironmental program behind HCC recurrence after incomplete radiofrequency ablation

Davide Povero^1,2, Chun-Ming Wong^3,4

¹Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.

Hepatology (Baltimore, Md.)

|March 18, 2026

Summary

No abstract available in PubMed .

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