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Evidence for lineage-associated differences in Tembusu virus pathogenicity in avian hosts

Tao Wang1, Yuyan Fan2, Fan Liu2

  • 1Institute of Veterinary Medicine and Immunology, Sichuan Agricultural University, Chengdu, Sichuan 611130, China; Research Center of Avian Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China; Agricultural Animal Diseases and Veterinary Public Health Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China; Engineering Research Center of Southwest Animal Disease Prevention and Control Technology for Ministry of Education, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.

Poultry Science
|March 18, 2026
PubMed
Summary

Tembusu virus (TMUV) pathogenicity varies by evolutionary cluster and host species. Duck-origin Cluster 2.1 strains are most virulent in ducklings, while Cluster 2.2 shows high in vitro replication but low in vivo virulence.

Keywords:
ChicksDucklingsPathogenicityPhylogeneticsTembusu virus

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