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Published on: December 3, 2015
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Origami Robotics in Biomedical Applications: A Paradigm Shift in Design and Innovation
1Department of Mechanical Engineering, King Fahd University of Petroleum and Minerals, 31261, Dhahran, Saudi Arabia. ammar.alzaydi@kfupm.edu.sa.
Annals of Biomedical Engineering
|March 19, 2026
Summary
Origami robotics offers compact, adaptable devices for minimally invasive surgery and diagnostics. Future research aims to improve biocompatibility and control for clinical use.
Area of Science:
- Biomedical Engineering
- Robotics
- Materials Science
Background:
- Origami robotics integrates folding principles with robotic actuation for advanced biomedical applications.
- These systems address challenges in surgery, diagnostics, and drug delivery through miniaturization and adaptability.
Purpose of the Study:
- To review recent advancements in origami-inspired biomedical systems.
- To highlight design, fabrication, and translational potential of these technologies.
Main Methods:
- A narrative review of peer-reviewed literature from 2010-2025.
- Searches conducted in Scopus, PubMed, and IEEE Xplore using keywords like 'origami robotics' and 'minimally invasive systems'.
Main Results:
- Origami architectures enable extreme miniaturization, flexibility, and deployable geometries for improved surgical access and functionality.
- Applications span minimally invasive surgery, targeted drug delivery, diagnostics, and rehabilitation.
- Key trends include smart materials, programmable stiffness, and self-folding mechanisms.
Conclusions:
- Origami robotics is pivotal for next-generation biomedical devices.
- Future work should focus on bioresponsive materials, adaptive controls, and regulatory frameworks for clinical translation.
