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Intrauterine Drug Delivery Systems

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...

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Related Experiment Video

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Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells

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Published on: February 9, 2019

Profile of Long Acting Reversible Contraceptive Users.

Shreyashi Aryal¹, Kristina Shakya¹, Prabesh Adhikari²

¹Department of Obstetrics and Gynecology, Kathmandu Medical College and Teaching Hospital , Sinamangal, Kathmandu, Nepal.

Journal of Nepal Health Research Council

|March 19, 2026

Summary

The subdermal implant is the most chosen long-acting reversible contraceptive (LARC). Socio-demographic factors like caste and education significantly influence women's LARC choices.

Keywords:

Contraception; drug implant; intrauterine device; LARC.

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Area of Science:

Reproductive Health
Contraception
Sociology

Background:

Long-acting reversible contraceptives (LARCs) are safe and effective, crucial for increasing modern contraceptive use.
Women's reproductive health conditions and socio-economic background influence LARC utilization.
Understanding characteristics of women choosing LARCs is vital for reproductive health strategies.

Purpose of the Study:

To explore the characteristics of women of reproductive age who selected long-acting reversible contraceptive methods.
To identify factors influencing the choice of specific LARC methods.

Main Methods:

A cross-sectional study involving 74 women (15-49 years) at Kathmandu Medical College.
Convenience sampling and ethical approval were obtained.
Demographic and obstetric data were collected and analyzed using SPSS version 21 with descriptive statistics.

Main Results:

37.33% of women seeking contraception chose LARCs.
The subdermal implant was the most preferred LARC method.
Levonorgestrel intrauterine devices were preferred by older women (mean age 38) compared to copper IUDs (33.67) and subdermal implants (32.49).
The majority of users (66.21%) belonged to the Brahmin/Chhetri caste.

Conclusions:

The subdermal implant is the most favored Long Acting Reversible Contraceptive method.
Caste and education levels significantly impact contraceptive choices.
Socio-demographic and reproductive health factors play a crucial role in selecting long-term birth control methods.