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Updated: Mar 20, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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Difluoro(methoxy)methyl Is a Neglected Group for Medicinal Chemistry─Revival via CF2OMe-Containing Amines

Mykhailo O Pashko1,2, Dmitry S Granat1,3, Oleksii O Klymenko-Ulianov3,4

  • 1Enamine Ltd., 78 Winston Churchill str., 02094 Kyiv, Ukraine.

Organic Letters
|March 19, 2026
PubMed

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