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Updated: Jul 1, 2026

Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
Published on: October 16, 2013
Associations between physical fitness and idiopathic scoliosis in Chinese adolescents: A case-control study
Fangwen Zhang1,2, Wei Peng2, Zikang Zhang1,2
1University of Science and Technology of China, Hefei 230026, China.
Objective:
Adolescent idiopathic scoliosis (AIS) screening and physical fitness testing are important components of health management for Chinese adolescents. This study aimed to evaluate the independent associations between prior-year physical fitness scores and AIS, with sex-stratified analysis.
Methods:
This case-control study was conducted in Jincheng, Shanxi Province, China, from March to October 2025, including 401 cases of AIS aged 13-18 years and 820 healthy controls matched to the cases by age and sex. Multiple logistic regression was used to evaluate the independent associations between prior-year physical fitness and AIS.
Results:
In the male subgroup, for each 1 kg/m2 increase in BMI, the odds of AIS decrease by 8.2%; for each 10-point increase in vital capacity, 50 m run, and sit-and-reach score, the odds of AIS decrease by 14.4%, 16.3%, and 23.8%, respectively. In the female subgroup, for each 1 kg/m2 increase in BMI, the odds of AIS decrease by 9.2%; for each 10-point increase in vital capacity and standing long jump score, the odds of AIS decrease by 12.7% and 9.6%, respectively.
Conclusions:
This study suggests incorporating physical fitness monitoring into the AIS screening and preventive strategies.

