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Temporal changes in quadriceps and hamstring strength and flexibility following total knee arthroplasty
Saidan Shetty1, Bincy M George2, Mohandas Rao Kg2
1Department of Anatomy, Melaka Manipal Medical College- Manipal Campus, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.
Journal of Orthopaedics
|March 19, 2026
Summary
Quadriceps and hamstring strength and flexibility improve after total knee arthroplasty (TKA), but deficits persist. Early, progressive rehabilitation focusing on long-term quadriceps strengthening and flexibility is crucial for optimal recovery after TKA.
Area of Science:
- Orthopedics and Rehabilitation Science
- Biomedical Engineering
- Kinesiology
Background:
- Quadriceps and hamstring dysfunction are common in knee osteoarthritis (OA) and after total knee arthroplasty (TKA).
- Muscle flexibility changes and their impact on postoperative recovery after TKA are not well understood.
- Strength deficits are frequently studied, but flexibility requires further investigation.
Purpose of the Study:
- To evaluate temporal changes in quadriceps and hamstring strength and flexibility.
- To compare these changes from preoperatively to one year after TKA.
- To compare outcomes with healthy controls.
Main Methods:
- Assessed quadriceps and hamstring strength using a handheld dynamometer.
- Measured flexibility using standardized muscle length tests.
- Collected data preoperatively and at 6 weeks, 3, 6, and 12 months post-TKA, comparing with healthy controls.
Main Results:
- Preoperatively, both strength measures were significantly lower than controls.
- Strength declined further at 6 weeks post-TKA, especially quadriceps.
- While strength and flexibility improved significantly from 3 to 12 months, they remained lower than controls at 12 months.
Conclusions:
- Quadriceps and hamstring strength and flexibility improve significantly in the first year after TKA.
- Residual quadriceps deficits persist compared to healthy individuals.
- Early, progressive rehabilitation emphasizing long-term quadriceps strengthening and flexibility is recommended for optimal TKA outcomes.

