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Comparative Healing Outcomes of Periapical Lesions with Different Histopathological Features Following Endodontic
Osama Magdy Monir Mostafa1, Kavita Pankaj Sonwane2, Danish Muzaffar3
1Department of Conservative and Endodontics, Almoosa Specialist Hospital, Alahsa, Kingdom of Saudi Arabia.
Aim:
This study aimed to compare the healing outcomes of periapical lesions with different histopathological features, focusing on the effectiveness of nonsurgical endodontic therapy versus surgical management.
Methodology:
This observational study compared the healing of histologically confirmed periapical lesions after nonsurgical or surgical treatment. Patients were followed for ≥12 months. Healing was assessed clinically and radiographically at 6 and 12 months and classified as complete, incomplete, or no healing. Chi-square tests compared outcomes between treatment groups (P < 0.05).
Results:
Analysis revealed that nonsurgical management showed high success in periapical granulomas and pocket cysts, whereas surgical approaches provided superior outcomes in true cysts and persistent lesions. A comparative table demonstrated that complete healing was significantly more predictable when treatment modality was tailored to the lesion's histopathology.
Conclusion:
Histopathological differentiation of periapical lesions plays a critical role in guiding treatment strategy. While nonsurgical therapy remains effective for most inflammatory lesions, surgical intervention is more beneficial for true cysts, underscoring the importance of lesion-specific management.
