Related Experiment Video
Updated: Mar 20, 2026

Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy
Published on: June 25, 2013
Study of Respiratory and Hemodynamic Variables in Patients Receiving either Volume Control Ventilation or Pressure
Ruchi Tandon1, Tahir A Khan1, Chitra Bansal2
1Department of Emergency Medicine, Gandhi Medical College, Bhopal, Madhya Pradesh, India.
Objective:
To evaluate respiratory and hemodynamic variables in patients receiving volume-controlled ventilation (VCV) versus pressure-controlled ventilation (PCV) during laparoscopic surgeries.
Methods:
Sixty ASA grade I-II patients, aged 18-60 years, with a body mass index (BMI) under 30, scheduled for elective laparoscopic procedures, were enrolled. Group A was sustained on VCV, but Group B transitioned to PCV after 15 min of VCV. Ventilation parameters were established with a tidal volume of 6 mL/kg, a respiratory rate of 12 breaths per minute, and a PEEP of 5 cm H₂O. Hemodynamic and respiratory parameters (systolic and diastolic blood pressure (SBP, DBP), MAP, heart rate (HR), oxygen saturation (SpO₂), capnography (EtCO₂), and peak airway pressure (Ppeak)) were documented at intervals of 15 min.
Results:
Group A exhibited markedly elevated heart rate and mean arterial pressure (MAP) at multiple intervals (P < 0.05). EtCO₂ levels were comparable between groups, except upon extubation, where Group B exhibited lower levels. Ppeak levels were significantly elevated with VCV after 30 min (P < 0.001).
Conclusion:
PCV demonstrated reduced lower airway pressures and enhanced hemodynamic stability relative to VCV in non-obese ASA I-II individuals.
Related Concept Videos
Mechanical Ventilation I: Indication and Settings
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Respiratory Volumes
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...

