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Related Experiment Video

Updated: Mar 20, 2026

Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications

Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications

Published on: August 30, 2018

3D-printed syringe holder with synchronized push-pull action.

Daniel P G Nilsson¹, Magnus Andersson^1,2

¹Department of Physics, Umeå University, Umeå, 901 87, Sweden.

|March 19, 2026

Summary

This summary is machine-generated.

A new 3D-printed Push2Pull syringe holder synchronizes two syringes for precise, constant-volume liquid exchange. This low-cost, open-source device eliminates the need for expensive pumps, making it ideal for various experimental settings.

Keywords:

Culture medium Design-build-test Fluid exchange Push2Pull Syringe holder Syringe pump

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Last Updated: Mar 20, 2026

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Area of Science:

Biotechnology
Chemical Engineering
Laboratory Equipment

Background:

Controlled liquid exchange is crucial for many biological and chemical experiments.
Electronic syringe pumps are often expensive and complex for push-pull configurations.
There is a need for accessible, cost-effective fluid handling solutions.

Purpose of the Study:

To develop a simple, low-cost device for synchronized, constant-volume liquid exchange.
To provide an alternative to electronic syringe pumps for fluid handling.
To create an open-source solution for precise fluid exchange.

Main Methods:

Designed and 3D-printed the Push2Pull syringe holder.
Mechanically synchronized two standard disposable syringes (1-60 mL).
Validated exchange accuracy and used CFD simulations for efficiency analysis.

Main Results:

Achieved exchange accuracy within ±2% v/v across the full travel range.
Device operates without electricity or additional hardware.
Material cost for the device is less than $10.

Conclusions:

The Push2Pull syringe holder is an accessible, open-source solution for precise fluid handling.
It offers a cost-effective and simple alternative to electronic pumps.
Suitable for both laboratory and field applications requiring controlled liquid exchange.