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Antigen detection of Talaromyces infection in the US: Case report
Emily E Evans1, Jennifer Spicer1, Vince Marconi1
1Emory University, 100 Woodruff Circle, Atlanta, GA, 30321, United States of America.
Abstract:
Talaromycosis is an invasive fungal infection endemic in Southeast Asia and has emerged as a leading cause of HIV-related death in the highly endemic countries of Vietnam, Thailand and China. Travel-related cases have been increasingly reported in immunocompromised people since the 1980s. Lack of clinical suspicion and non-culture-based diagnostics prevent timely, accurate diagnosis and treatment. Here we describe a travel-related case of talaromycosis in whom the diagnosis was confirmed using Mp1p antigen detection, highlighting its clinical utility.
Insights
Talaromycosis, an invasive fungal infection, is a significant cause of HIV-related death in Southeast Asia. Early diagnosis, aided by Mp1p antigen detection, is crucial for effective treatment of this travel-related illness.
Area of Science:
- Mycology
- Infectious Diseases
- Clinical Diagnostics
Background:
- Talaromycosis is an invasive fungal infection prevalent in Southeast Asia.
- It is a major cause of death among individuals with HIV in endemic regions like Vietnam, Thailand, and China.
- Increasingly reported travel-related cases affect immunocompromised individuals globally.
