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Related Experiment Video

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Robot-Assisted Peripheral Retinal Visualization during Vitrectomy without Scleral Depression: A First-In-Human

Kenta Ashikaga1,2, Yoshihito Sakanishi1,2, Toshiaki Hirakata1,2

  • 1Department of Ophthalmology, Juntendo University Graduate School of Medicine, Tokyo, Japan.

Ophthalmology Science
|March 19, 2026
PubMed
Summary

Robot-assisted peripheral retinal visualization using the OQrimo system is feasible and safe for vitrectomy surgery. This new method shows comparable short-term outcomes to traditional techniques, despite longer operation times.

Keywords:
EndoscopeEpiretinal membraneRobot surgeryRoboticsVitrectomy.

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Area of Science:

  • Ophthalmology
  • Surgical Technology
  • Medical Robotics

Background:

  • Peripheral retinal visualization is crucial during vitrectomy.
  • Conventional methods often require scleral depression, which can be uncomfortable.
  • New technologies aim to improve visualization and patient comfort.

Purpose of the Study:

  • To assess the feasibility and short-term safety of the OQrimo intraocular endoscope-holding robot for peripheral retinal visualization.
  • To compare robot-assisted visualization without scleral depression to conventional methods during vitrectomy.

Main Methods:

  • A prospective, nonrandomized, comparative study involving 16 patients undergoing vitrectomy.
  • Eight eyes used the OQrimo system (robot group), and 8 used conventional visualization (control group).
  • Outcomes included visualization range, postoperative inflammation, pain, surgical time, wound healing, and complications.

Main Results:

  • Robot-assisted visualization was successful in 87.5% of cases.
  • Postoperative inflammation was similar between groups.
  • Surgical time was significantly longer in the robot group (56.0 min vs. 36.5 min).
  • No major complications were observed in either group.

Conclusions:

  • Robot-assisted peripheral retinal visualization without scleral depression is technically feasible.
  • The OQrimo system offers a comparable short-term safety profile to conventional surgery.
  • Longer operative times were noted in this initial series, requiring further optimization.