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Related Concept Videos

Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Pulmonary Tuberculosis IV01:26

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Tuberculosis I01:29

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Pulmonary Tuberculosis II01:28

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Related Experiment Video

Updated: Mar 21, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

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Sirolimus Therapy in Generalized Lymphatic Anomaly With Tuberculosis: A Case Report.

Kamal K Singhal1, Piali Mandal1, Varinder Singh1

  • 1Department of Pediatrics, Lady Hardinge Medical College & Kalawati Saran Children's Hospital, New Delhi, India.

Pediatric Pulmonology
|March 19, 2026
PubMed
Summary

This case study details a rare instance of Generalized Lymphatic Anomaly (GLA) co-occurring with tuberculosis in a pediatric patient. Combined sirolimus and anti-tubercular therapy led to sustained clinical improvement.

Keywords:
chylothoraxgeneralized lymphatic anomalypleural effusion

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Last Updated: Mar 21, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

748

Area of Science:

  • Pediatric Medicine
  • Vascular Anomalies
  • Infectious Diseases

Background:

  • Generalized Lymphatic Anomaly (GLA) is a rare condition affecting lymphatic vessels.
  • Tuberculosis can present with diverse clinical manifestations, including pleural effusions.
  • Co-occurrence of GLA and tuberculosis is exceptionally rare.

Purpose of the Study:

  • To report a unique case of a critically ill child with coexisting Generalized Lymphatic Anomaly and tuberculosis.
  • To highlight the diagnostic and therapeutic challenges in managing dual pathology.
  • To emphasize the importance of considering concurrent infections in complex pediatric cases.

Main Methods:

  • Clinical case presentation of a 14-year-old female.
  • Diagnostic workup including radiological evaluation and pleural fluid cultures.
  • Therapeutic interventions involving medications for GLA and tuberculosis.

Main Results:

  • Radiological diagnosis of Generalized Lymphatic Anomaly (GLA) was established.
  • Pleural fluid analysis revealed Mycobacterium tuberculosis.
  • Combined treatment with sirolimus and anti-tubercular therapy (ATT) resulted in sustained clinical improvement.

Conclusions:

  • This case underscores the rare coexistence of Generalized Lymphatic Anomaly and tuberculosis.
  • Persistent pleural effusions in children warrant consideration for dual pathology.
  • Multifaceted treatment approaches are crucial for managing complex pediatric conditions.