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Comparison of Kleihauer-Betke Methodology Performed by Experienced Morphologists and Flow Cytometry in Fetomaternal

Miles Ma1, Alireza Ardjmand2, Nisha Aloysious1

  • 1Department of Haematology, NSW Health Pathology, Prince of Wales Hospital, Randwick, New South Wales, Australia.

International Journal of Laboratory Hematology
|March 19, 2026
PubMed
Abstract

No abstract available in PubMed .

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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