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VIGICANCER, a childhood cancer surveillance system in Colombia, collects vital data to improve cancer control. The system

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Area of Science:

  • Pediatric Oncology
  • Public Health Surveillance
  • Epidemiology

Background:

  • Population-based cancer surveillance systems are crucial for cancer control but are scarce in low- and middle-income countries (LMICs).
  • Colombia implemented VIGICANCER in 2009, a nationwide childhood cancer clinical outcomes surveillance system, to address this data gap.
  • VIGICANCER aims to collect, analyze, and disseminate valid, reliable, and timely population-based information on childhood cancer.

Purpose of the Study:

  • To describe the evolution and impact of VIGICANCER, a nationwide childhood cancer clinical outcomes surveillance system in Colombia.
  • To analyze clinical characteristics, overall survival (OS), and event-free survival (EFS) in a 14-year cohort of Colombian children with cancer.
  • To provide a reproducible, equity-focused model for LMICs to inform cancer control policy and reduce survival disparities.

Main Methods:

  • VIGICANCER registers children (<19 years) newly diagnosed with cancer receiving treatment at participating institutions.
  • Quarterly active follow-up surveillance collects sociodemographic and clinical data, documenting deaths, relapses, second malignancies, treatment abandonment, and loss to follow-up.
  • Kaplan-Meier and log-rank tests were used for survival analyses on data from 2009 to 2023.

Main Results:

  • VIGICANCER has collected data from over 12,000 patients, covering 55%-60% of projected childhood cancer cases annually.
  • From 2009 to 2023, 9,986 patients were analyzed, with 3,626 events including 3,081 deaths.
  • The 5-year overall survival (OS) was 63.3% and event-free survival (EFS) was 57.9% for the cohort.

Conclusions:

  • VIGICANCER yields actionable population-based data that guides interventions to improve childhood cancer survival in Colombia.
  • The system provides a reproducible model for LMICs to implement effective cancer surveillance.
  • Real-world data from VIGICANCER informs cancer control policy, aiming to reduce survival disparities and advance global childhood cancer initiatives.