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Differences in Optic Pathway Glioma Prevalence Among Children with Neurofibromatosis Type 1
Danae Kokossis1, Ethan Hillis2, Jenny P Garzon3
1Department of Pediatrics, St. Louis Children's Hospital and Washington University, St. Louis, MO.
The Journal of Pediatrics
|March 19, 2026
Abstract
None:
This multi-institutional, natural language processing-based analysis of 273 children with neurofibromatosis 1-associated optic pathway gliomas examines the impact of ancestral background on clinical presentation and progression. We report that White children had a greater prevalence of optic pathway glioma than Black or Asian children, but clinical features and outcomes did not differ across groups.
Keywords:
NF1ancestral backgroundneurofibromatosisoptic pathway gliomapediatric gliomapopulation differences
