[Experimental pancreas transplantation in swine]

After surveying the problem of pancreas transplantation the results of pancreatico-duodenal transplantation attempts performed on dogs and 20 pigs are reported. Surgically, the major pancreatic duct is anastomosed to a Roux' loop using a preserved duodenal patch around the papilla. The graft is sited unto the retroperitoneal space. The animals survived for 6 to 9 months. In some cases an increasing fibrosis of the transplantate was observed. Most often, the animals died from pneumonia. The authors want to continue their research in order to obtain better results.