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An Unusual Mid-Ventricular Takotsubo Cardiomyopathy: A Case Report.
Ibrahim Antoun1,2, Ayman Helal1, Momen Ali1
1Department of Cardiology Kettering General Hospital Kettering UK.
Clinical Case Reports
|March 20, 2026
Summary
Mid-ventricular Takotsubo cardiomyopathy (TTC), a rare stress-induced heart condition, was diagnosed in a patient presenting with ACS-like symptoms. Cardiac MRI confirmed the diagnosis, highlighting the importance of advanced imaging for this atypical TTC variant.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Internal Medicine
Background:
- Takotsubo cardiomyopathy (TTC), or stress cardiomyopathy, presents with transient heart wall motion abnormalities mimicking acute coronary syndrome (ACS).
- The mid-ventricular variant of TTC is rare and poses diagnostic challenges due to its atypical presentation.
- Distinguishing TTC from other myocardial conditions is crucial for appropriate patient management.
Purpose of the Study:
- To present a case of an uncommon mid-ventricular Takotsubo cardiomyopathy.
- To highlight the diagnostic utility of multimodal cardiac imaging, particularly cardiac magnetic resonance (CMR).
- To emphasize the importance of differentiating atypical TTC from other myocardial pathologies.
Main Methods:
- Case presentation of a 77-year-old female with symptoms suggestive of ACS.
- Coronary angiography to exclude obstructive coronary artery disease.
- Multimodal cardiac imaging, including echocardiography and cardiac magnetic resonance (CMR), for detailed myocardial assessment.
Main Results:
- Coronary angiography showed no significant coronary artery obstructions.
- Cardiac magnetic resonance (CMR) revealed circumferential mid-ventricular hypokinesis with sparing of apical and basal segments.
- Diagnosis of mid-ventricular Takotsubo cardiomyopathy (TTC) was confirmed by imaging findings.
Conclusions:
- This case highlights the diagnostic challenges and importance of advanced imaging in identifying rare TTC variants.
- Echocardiography and CMR are invaluable tools for differentiating mid-ventricular TTC from other myocardial diseases.
- The patient achieved full clinical recovery and normalization of cardiac function, underscoring the generally favorable prognosis of TTC.
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