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Lipedema Reduction Surgery Outcomes and Comorbidities: A Retrospective Study
Jaime S Schwartz1, Noah Danesh2, Eva Danesh3
1From the Private Practice, Total Lipedema Care, Beverly Hills, CA.
Plastic and Reconstructive Surgery. Global Open
|March 20, 2026
Summary
The SMiLE technique significantly reduces pain and improves mobility for lipedema patients. This lipedema reduction surgery offers a comprehensive approach to managing the condition, enhancing quality of life.
Area of Science:
- Adipose tissue disorders
- Surgical techniques
- Patient-reported outcomes
Background:
- Lipedema is a progressive disorder of subcutaneous adipose tissue, primarily affecting women.
- It causes painful nodules and inflammation, leading to impaired mobility and reduced quality of life.
- Current nonsurgical treatments provide limited relief, necessitating further interventions.
Purpose of the Study:
- To evaluate the efficacy of the SMiLE (Softening, Mobilization, Liposuction, Extraction) technique for lipedema reduction surgery (LRS).
- To assess the impact of SMiLE on pain, daily activities, and quality of life in lipedema patients.
Main Methods:
- A study involving sixty-two women who underwent LRS using the SMiLE technique.
- Data collected via online survey on medical history, comorbidities, and pre- and post-surgery outcomes.
- Outcome measures included pain levels, activities of daily living, and quality of life.
Main Results:
- Significant improvements observed in patients' daily lives post-surgery.
- Average pain reduction of 73.9%, with 81.3% reduction in the buttock shelf area.
- Mobility improved in 93% of participants; quality of life improved by 47.5%.
Conclusions:
- The SMiLE technique effectively removes lipedema tissue, offering an advancement in surgical management.
- It reduces pain, improves mobility, and alleviates physical and psychological burdens associated with lipedema.
- SMiLE can be considered a valuable option within a comprehensive lipedema treatment strategy.

