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Transmesenteric Laparoscopic Pyeloplasty in Trendelenburg Position for Horseshoe Kidney with Hydronephrosis
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INFANTILE HYPERTROPHIC PYLORIC STENOSIS IN NIGERIA: A MULTICENTER RETROSPECTIVE STUDY

D Olulana1, F Kumolalo1,2, A Ajao1,3

  • 1Department of Surgery, University College Hospital, Ibadan, Nigeria.

Annals of Ibadan Postgraduate Medicine
|March 20, 2026
PubMed

Insights

Infantile hypertrophic pyloric stenosis (IHPS) affects infants worldwide. This Nigerian study found similar IHPS epidemiology and good outcomes compared to global data, with longer symptom duration linked to mortality.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Epidemiology

Background:

  • Infantile hypertrophic pyloric stenosis (IHPS) exhibits variable incidence globally.
  • This study focuses on IHPS epidemiology, clinical presentation, and management in Nigeria.

Purpose of the Study:

  • To analyze the epidemiology of IHPS in Nigeria.
  • To describe the clinical presentation and management of IHPS.
  • To assess outcomes and identify factors influencing complications and mortality.

Main Methods:

  • Retrospective analysis of 131 IHPS cases across six Nigerian pediatric surgical centers.
  • Data collected and analyzed using descriptive statistics and Spearman's correlation (p < 0.05).

Main Results:

  • IHPS predominantly affected male infants (M:F ratio 5:1), with a median age of 6 weeks.
  • Electrolyte disturbances were common (48.1%), including hyponatremia and hypokalemia.
  • Peri-operative mortality was 5.3%; longer symptom duration, jaundice, and elevated creatinine correlated with complications and mortality.

Conclusions:

  • Nigerian IHPS epidemiology and clinical presentation align with international findings.
  • Outcomes are comparable to other Low Middle Income Countries, demonstrating good post-operative results.
  • Early presentation is crucial to minimize complications and mortality in IHPS patients.
Abstract

Keywords:
AfricansIncidenceInfantilePyloric stenosis.

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