Comparison of Visual Performance and Patient Satisfaction Between Two Trifocal Intraocular Lenses: A Prospective,...

Area of Science:

• Ophthalmology
• Biomedical Engineering
• Optics

Background:

• Cataract surgery aims to restore vision, with intraocular lenses (IOLs) replacing the clouded natural lens.
• Advanced trifocal IOLs offer solutions for presbyopia, aiming for spectacle independence across multiple visual distances.
• Comparing different trifocal IOL platforms is crucial for understanding their distinct visual performance characteristics.

Purpose of the Study:

• To compare the visual performance, patient-reported outcomes, and spectacle independence of two advanced trifocal IOLs: Clareon PanOptix and TECNIS Odyssey.
• To investigate if optical design differences between PanOptix and Odyssey IOLs result in varying strengths in visual acuity (VA) and contrast sensitivity (CS).
• To assess patient satisfaction and photic phenomena associated with each IOL platform.

Main Methods:

• Prospective, single-center, single-surgeon trial involving 19 patients (38 eyes) undergoing bilateral cataract surgery.
• Paired-eye design with randomization for IOL allocation (PanOptix in one eye, Odyssey in the fellow eye).
• Postoperative assessments included monocular distance, intermediate, and near visual acuity, uncorrected visual acuities, residual refraction, contrast sensitivity, and patient-reported outcomes.

Main Results:

• The TECNIS Odyssey IOL demonstrated significantly better distance-corrected and uncorrected distance visual acuity (CDVA and UCDVA) compared to PanOptix.
• The Clareon PanOptix IOL showed superior intermediate visual acuity (DCIVA) compared to Odyssey.
• Odyssey eyes exhibited significantly higher contrast sensitivity (CS); however, no significant differences were found in near visual acuity or rates of photic phenomena (starburst, halo, glare). Spectacle independence was high (89.47%) for both IOLs.

Conclusions:

• Clareon PanOptix IOL offers superior intermediate visual acuity, while TECNIS Odyssey IOL provides better distance visual acuity and contrast sensitivity.
• Both advanced trifocal IOL platforms are viable options for cataract surgery, achieving high spectacle independence.
• The choice between PanOptix and Odyssey may depend on the patient's visual needs and priorities regarding specific visual distances and visual quality.