Short-Term Intraocular Pressure Changes After 0.1% Fluorometholone in Pediatric Strabismus Surgery

Area of Science:

• Ophthalmology
• Pediatric Surgery
• Pharmacology

Background:

• Strabismus surgery in children can lead to postoperative inflammation.
• Intraocular pressure (IOP) monitoring is crucial after ophthalmic procedures.
• Fluorometholone ophthalmic solution (FM) is used for its anti-inflammatory properties.

Purpose of the Study:

• To evaluate the effect of 0.1% fluorometholone ophthalmic solution (FM) on intraocular pressure (IOP) in pediatric patients following strabismus surgery.

Main Methods:

• A study included 224 children (<15 years) who underwent strabismus surgery.
• Participants received FM four times daily for one month postoperatively.
• Intraocular pressure was measured using a non-contact tonometer, assessing pre- and postoperative IOP, and changes.

Main Results:

• Mean pre- and postoperative IOPs were 14.7 ± 2.4 mmHg and 14.8 ± 3.3 mmHg, respectively (p = 0.552).
• 3.6% of eyes showed an IOP increase of >6 mmHg.
• 6.3% of eyes had a postoperative IOP >20 mmHg.

Conclusions:

• Short-term use of FM did not significantly elevate IOP in pediatric patients post-strabismus surgery.
• FM appears to be a safe option for managing inflammation after this procedure in children.