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Short-Term Intraocular Pressure Changes After 0.1% Fluorometholone in Pediatric Strabismus Surgery

Kenta Hozumi1, Teiji Yagasaki1,2, Yoshimi Yokoyama1

  • 1Department of Ophthalmology, Japan Community HealthCare Organization (JCHO) Chukyo Hospital, Nagoya, Aichi, Japan.

Clinical Ophthalmology (Auckland, N.Z.)
|March 20, 2026
PubMed

Insights

Short-term use of fluorometholone ophthalmic solution (FM) after pediatric strabismus surgery did not significantly increase intraocular pressure (IOP). This anti-inflammatory treatment is considered safe for children, with minimal IOP elevation observed post-surgery.

Area of Science:

  • Ophthalmology
  • Pediatric Surgery
  • Pharmacology

Background:

  • Strabismus surgery in children can lead to postoperative inflammation.
  • Intraocular pressure (IOP) monitoring is crucial after ophthalmic procedures.
  • Fluorometholone ophthalmic solution (FM) is used for its anti-inflammatory properties.

Purpose of the Study:

  • To evaluate the effect of 0.1% fluorometholone ophthalmic solution (FM) on intraocular pressure (IOP) in pediatric patients following strabismus surgery.

Main Methods:

  • A study included 224 children (<15 years) who underwent strabismus surgery.
  • Participants received FM four times daily for one month postoperatively.
  • Intraocular pressure was measured using a non-contact tonometer, assessing pre- and postoperative IOP, and changes.

Main Results:

  • Mean pre- and postoperative IOPs were 14.7 ± 2.4 mmHg and 14.8 ± 3.3 mmHg, respectively (p = 0.552).
  • 3.6% of eyes showed an IOP increase of >6 mmHg.
  • 6.3% of eyes had a postoperative IOP >20 mmHg.

Conclusions:

  • Short-term use of FM did not significantly elevate IOP in pediatric patients post-strabismus surgery.
  • FM appears to be a safe option for managing inflammation after this procedure in children.
Abstract

Keywords:
pediatric ophthalmologypostoperative complicationsteroid responderstrabismus surgerysubconjunctival dexamethasone

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