Assessment of Peripheral Anterior Synechiae Using Linear Gonio-Images Following Trabeculotomy with Trabectome

Area of Science:

• Ophthalmology
• Glaucoma Surgery
• Anterior Segment Imaging

Background:

• Trabectome surgery is a common procedure for glaucoma management.
• Peripheral anterior synechiae (PAS) can affect intraocular pressure (IOP) and surgical outcomes.
• Quantifying PAS post-surgery is crucial for understanding long-term efficacy.

Purpose of the Study:

• To quantify the extent of peripheral anterior synechiae (PAS) after Trabectome surgery using automated gonioscopy (GS-1).
• To evaluate the effect of quantified PAS on intraocular pressure (IOP) reduction following Trabectome surgery.

Main Methods:

• Retrospective, single-center study of patients undergoing Trabectome surgery.
• Automated gonioscopy (GS-1) used at 6 and 12 months postoperatively to measure PAS extent.
• Analysis of covariance (ANCOVA) and Spearman correlation used to assess IOP reduction, PAS extent, and preoperative factors.

Main Results:

• Automated gonioscopy revealed significant PAS in all analyzed eyes at 6 and 12 months.
• Mean PAS extent did not significantly change between 6 and 12 months (approx. 40-44%).
• Only preoperative IOP significantly correlated with IOP reduction; PAS extent showed limited correlation.

Conclusions:

• Trabectome surgery is associated with widespread PAS detected by automated gonioscopy.
• The extent of PAS appears to have a limited impact on IOP reduction after this procedure.
• Further research is needed to clarify the long-term implications of PAS following Trabectome surgery.