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A Mouse Model of Retinal Ischemia-Reperfusion Injury Through Elevation of Intraocular Pressure
Published on: July 14, 2016
[Expression of Concern] Fasudil, a Rho‑associated protein kinase inhibitor, attenuates retinal ischemia and
1Department of Ophthalmology, Shengjing Hospital Affiliated to China Medical University, Shenyang 110004, P.R. China.
Abstract:
Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the photomicrographs shown in Fig. 1 on p. 195, the 'I/R' and 'Control' data panels (for the Day 1 experiments) contained an overlapping section, such that data which were intended to show the results of differently performed experiments were apparently derived from the same original source. The authors have been contacted by the Editorial Office to offer an explanation for the apparent anomaly in the presentation of the data in their paper, and we are awaiting their response. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [International Journal of Molecular Medicine 28: 193‑198, 2011; DOI: 10.3892/ijmm.2011.659].
Insights
An investigation is underway regarding potential issues with photomicrograph data presentation in a published paper. The Editorial Office is examining data integrity concerns raised by a reader.
Area of Science:
- Molecular Medicine
- Scientific Publishing
Background:
- A reader raised concerns about photomicrograph data in Fig. 1.
- Specific panels ('I/R' and 'Control' for Day 1) showed overlapping sections.
Purpose of the Study:
- To address potential data integrity issues in a published scientific paper.
- To notify readers of an ongoing investigation into data presentation anomalies.
Main Methods:
- Editorial review of photomicrograph data.
- Contacting authors for explanation of data anomalies.
Main Results:
- Apparent overlap in data panels suggests data may originate from the same source.
- Authors have been contacted for clarification.
Conclusions:
- An Expression of Concern has been issued due to potential scientific integrity issues.
- The investigation into the photomicrograph data presentation is ongoing.
