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Development and Validation of a Visual Grading Score of Disease Severity From Gait Videos in Genetic Peripheral

Helena F Pernice1,2, Emanuele Piazza3, Eleonora Asaad1

  • 1Klinik für Neurologie mit Experimenteller Neurologie, Charité Universitätsmedizin Berlin, Berlin, Germany.

European Journal of Neurology
|March 20, 2026
PubMed

Keywords:
Charcot–Marie–Tooth diseasegaitoutcome assessment, health careperipheral nervous system diseasestelemedicine

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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